Simplest things are usually hardest

I was doing some background research related to a comparison of continuous variables when sample size is sufficiently small. I came up with this paper by de Winter titled Using the Student’s t-test with extremely small sample sizes. I viewed the relevant results and when I got to the very final sentence of the paper I had to stop. What did I just read? Well, this:

Finally, researchers should always judge the credibility of their findings and should remember that extraordinary claims require extraordinary evidence.

de Winter (2013)

If only researchers in biomedicine had this little advice in their mind, things would be very different. Judging the credibility is something which is done extremely rarely. I hope that will change in the future once we start to embrace variation and accept uncertainty.

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